Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment.

نویسندگان

  • E L Lee
  • H H Bendre
  • A Kalmykov
  • J Y Wong
چکیده

Current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype. We modified a commercially available product for uniaxial cell sheet conditioning with thermoresponsive copolymers. Thus, culture of detachable conditioned cell sheets is shortened while retaining structural integrity and contractility.

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عنوان ژورنال:
  • Journal of materials chemistry. B

دوره 3 40  شماره 

صفحات  -

تاریخ انتشار 2015